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Cystic fibrosis in adults. Diagnostic, epidemiologic and quality-of-life aspects


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Title: Cystic fibrosis in adults. Diagnostic, epidemiologic and quality-of-life aspects
Authors: Gilljam, Marita 1956-
Issue Date: 2007
University: Göteborgs universitet/University of Gothenburg
Institution: Department of Internal Medicine
Avdelningen för invärtesmedicin
Date of Defence: 2007-03-30
Disputation: Aulan, Jubileumskliniken, Sahlgrenska Sjukhuset, kl. 13.00
Publication type: Doctoral thesis
Keywords: Cystic fibrosis
cystic fibrosis transmembrane conductance regulator
pregnancy
male infertility
bronchoalveolar lavage
quality of life
questionnaire
Abstract: Background: Cystic fibrosis (CF) is a severe hereditary disease. The type of mutation in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene will determine the degree of CFTR chloride channel malfunction. Disturbed salt transport leads to production of sticky mucus, blocking exocrine gland ducts and persistent airway infection, starting early in life. Most patients are pancreatic insufficient, and almost all males are infertile due to obstruction of the vas deferens. Diagnostic c... more
ISBN: 978-91-628-7083-6
URI: http://hdl.handle.net/2077/17021
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

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