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Microarray analysis of gene expression in human adipocytes and adipose tissue
Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine ...
Molecular mechanisms in obesity-associated metabolic disease
Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. This thesis ...
Cardiovascular and metabolic control in obese children and adolescents
Childhood obesity is an emerging risk factor for disease and mortality worldwide. The cardiovascular consequences and prevention thereof need to be further investigated. Exercise and weight loss are well examined and ...
Interactions between nutrition, obesity and the immune system
There are several links between body fat and the immune system. For example, mice lacking activity of the pro-inflammatory interleukin-(IL)-1 and IL-6 develop obesity. Conversely, obesity is associated with adipose tissue ...
Identification and imaging of lipids in tissues using TOF-SIMS
Introduction: Normal lipid metabolism in the adipose tissue, skeletal muscle and aortic wall is important for the physiological function of these tissues. Dyslipidemia that is often associated with intake of high energy ...
Cytokines in Metabolic Functions
During infections, circulating cytokines are largely produced by immune cells. In healthy obese individuals, large parts of these circulating cytokines are produced in adipose tissue, for instance by macrophages that have ...