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The role of the complement system in ischemic stroke and neural plasticity
(2013-10-29)
Evidence from experimental animal studies suggests that complement activation in the brain is a “double-edged sword” as it exerts beneficial or detrimental effects depending on the context. Here, we assessed whether ...
The role of astrocytes in stroke, brain plasticity and neurogenesis
(2013-05-10)
Astrocytes, one of the most abundant and heterogeneous cell types in the central nervous system, fulfill many important roles in the healthy and injured brain. This thesis investigates the role of astrocytes in the neurogenic ...
Irradiation-induced injury to the juvenile brain -Roles of sex and inflammation
(2013-11-14)
Radiotherapy is commonly used in the treatment of pediatric malignancies, but unfortunately it is associated with negative side effects, both long-term and short-term. Negative side effects following cranial irradiation ...