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The protective role of Nrf2/Keap1 in neurological disease and oxidative stress-induced cell damage
(2013-05-22)
Oxidative stress is a common feature in the pathogenesis of many diseases, including neurodegenerative diseases like Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS). Nrf2 and Keap1 regulate an inducible ...
The role of astrocytes in stroke, brain plasticity and neurogenesis
(2013-05-10)
Astrocytes, one of the most abundant and heterogeneous cell types in the central nervous system, fulfill many important roles in the healthy and injured brain. This thesis investigates the role of astrocytes in the neurogenic ...