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Cognitive dysfunction studied in animal models of schizophrenia
Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ...
Conditional and non-conditional reward-related responses to alcohol - nicotinic mechanisms
The mesolimbic dopamine system is believed to mediate the positive reinforcing and rewarding effects of addictive drugs by increasing dopamine levels in its terminal area, the nucleus accumbens (nAc). Nicotinic acetylcholine ...