Search
Now showing items 61-70 of 440
Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C. elegans
(2021-10-29)
Cancer is a major cause of mortality throughout the world. Despite the effort of the scientific community, plenty remains to understand about the biology or genetics of cancer. In solid tumors often as many as 90-99% of ...
Methodological considerations in epidemiological studies in perinatal medicine
(2021-05-05)
This thesis is based on two projects, each consisting of two papers. In these two projects we investigated factors affecting the variability in gestational duration, and associations between maternal diet and neonatal ...
Pelvic floor dysfunction in nulliparous women
(2022-01-18)
Background: Pelvic floor dysfunction (PFD) is a public health problem affecting millions of women worldwide. In addition to personal suffering, it also creates an economic burden for health care systems and society. Parity ...
Effect of Probiotics on Caries-related Variables
(2021-10-05)
In relation to the caries disease, the aims of this thesis were to investigate the effect of probiotic drops on different caries-related variables in vivo (Papers I & III), on interference capability and genetic response ...
Word-finding difficulties in left hemisphere stroke, multiple sclerosis and Parkinson's disease - differences in symptom occurrence and effects of anomia treatment
(2021-11-11)
Word-finding difficulties, or anomia, are a common symptom in various conditions affecting the brain, such as stroke, multiple sclerosis (MS) or Parkinson’s disease (PD). The aim of this thesis is twofold: (i) to increase ...
Physicians' practices in sickness certification for common mental disorders - assessment of work capacity and communication with the patient's workplace
(2021-11-25)
Physicians are key stakeholders in the sickness certification process. The first aim of this thesis was to examine physicians’ sickness certification practices from two perspectives: the assessment of work capacity and ...
Osteoporosis in murine SLE - Treatment with a tissue-selective estrogen complex
(2021-10)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
affecting mainly young women. Almost every organ in the body can be
affected and SLE patients often suffer from co-morbidities such as
cardiovascular ...
Acute respiratory infections among children in the Democratic Republic of Congo - nasopharyngeal pathogens, antibiotic resistance and vaccination
(2020-09-29)
ABSTRACT
Acute Lower Respiratory Infections (ALRI) remain a leading cause of morbidity and mortality among children in the Democratic Republic of the Congo (DR Congo). The pneumococcal conjugate vaccine PCV13 was ...
Cancer in organ transplant recipients
(2021-08-27)
Tens of thousands of transplantations are performed around the world each year. Organ transplant recipients (OTR) are obliged to receive life-long medical treatment with immunosuppressive drugs to ensure graft function. ...
Transplantation of normal and decellularized syngeneic, allogeneic and xenogeneic cardiac tissue in mice and non-human primates
(2020-03-05)
Introduction
Because of the restricted inherent capacity of regeneration and healing, transplantation is the only treatment for end-stage heart failure but it has limitations of donor shortage and graft rejection. Cardiac ...