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Microarray analysis of gene expression in human adipocytes and adipose tissue
(2008-02-21)
Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine ...
Antibiotic Resistance and Fitness of Escherichia coli in the Infantile Commensal Microbiota
(2007-05-14)
Microbial resistance to antibiotics is a growing problem worldwide. Resistance develops not only in microbes which are the targets of the antibiotic treatment, but also in those belonging to the normal microbiota of the ...
Alzheimer’s Disease: effect of Tau-related genes on the pathology, neurochemistry and risk of disease
(2007-11-07)
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. The predominant sporadic form of AD is a genetically complex disorder probably involving a combination of genetic factors together with environmental ...
Photdynamic therapy for treatment of Acne Vulgaris in clinical studies; dose response and mode of action
(2009-04-30)
This thesis deals with the use of photodynamic therapy (PDT) for treatment of Acne Vulgaris. Acne Vulgaris is one of the most common skin disorders. Conventional treatments target the pathogenic factors and include a variety ...
Lower Urinary Tract symptoms in women - aspects on epidemiology and treatment
(2009-04-17)
Lower urinary tract symptoms in women – aspects on epidemiology and treatment
Lower urinary tract symptoms (LUTS) are common conditions that compromise a person’s quality of life and result in increased health care costs ...
A role of CD44 in atherosclerosis? Studies in mice and humans
(2009-01-12)
Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the ...
Analysis of Binding Events and Diffusion in Living Cells
(2007-03-06)
It is well known that diffusion is the main mode of transport in living cells, but the
consequences of diffusion in a complex cellular environment are not generally appreciated. In
this thesis, we have investigated several ...
Epidemiological analysis of viral infections as risk factors for multiple sclerosis
(2009-06-16)
Viral childhood diseases have been implicated in the pathogenesis of multiple sclerosis (MS).
Swedish mass vaccination programmes resulted in radical changes in the panorama of the
targeted infections. Vaccines against ...
Nasopharyngeal carcinoma: past, present and future directions
(2007-12-07)
Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients ...
Barns delaktighet genom besök hos närstående som vårdas på en intensivvårdsavdelning
(2006-11-27)
Syfte: Att undersöka och beskriva villkor och förutsättningar för minderåriga barn att vara delaktiga genom att besöka en närstående som vårdas på en intensivvårdsavdelning (IVA) samt hur vårdnadshavarna upplever sitt barns ...