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Now showing items 31-40 of 55
Acute and chronic peritonitis in peritoneal dialysis: neurogenic inflammation and citrate treatment
(2009-10-06)
The prevalent problems associated with peritoneal dialysis (PD) are ultrafiltration failure and peritonitis. During PD the patient is sustained on a state of intraperitoneal inflammation, which over time impairs structure, ...
Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)
Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ...
Molecular and cellular interactions on noble metal nanopatterned surfaces − applications towards bone, soft tissue and infection control
(2014-05-09)
Biomaterial-associated infection is recognised as one of the main risks for failure of medical devices. The presence of a foreign material in tissues has been suggested to compromise the ability of host cells to eradicate ...
Central and Peripheral Neuroendocrine Factors in Cancer-Associated Anorexia and Cachexia
(2015-11-26)
Cancer anorexia-cachexia syndrome (CACS) develops in response to tumor-host biochemical interactions. A loss of appetite (anorexia) and increased metabolism results in a progressive wasting of adipose and skeletal muscle ...
Vascular and metabolic effects of selective PDE-5 inhibition - clinical and experimental studies
(2015-02-13)
ABSTRACT
Vascular and metabolic effects of selective PDE-5 inhibition
Clinical and experimental studies
Lovisa Sjögren
Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, ...
Inflammation and Cell Profileration Following Perinatal Brain Injury
(2010-08-30)
Inflammation plays an important role in cerebral ischemic injury in the immature brain. The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) ...
In vitro wound healing characteristics of amelogenins
(2011-05-09)
Wound healing involves the co-ordinated actions of several cell types, soluble cell mediators and extracellular matrix (ECM). This research project intended to investigate the role of certain ECM proteins in different ...
A methodological platform to study molecular biocompatibility of biomaterials. Experimental and clinical studies
(2016-05-13)
The aim of this project was to develop a methodological platform in order to advance our scientific understanding of the mechanisms of osseointegration. Screw-shaped, titanium implants, with different surface properties, ...
Biomarkers in Multiple Sclerosis - Monitoring disease activity and treatment afficacy
(2018-03-21)
The pathophysiology of multiple sclerosis (MS) is complex with the presence of inflammation and neurodegeneration in all stages of the disease. The disease course, treatment response and outcome are highly variable in MS. ...
The percutaneous implant. The effects of design, host site and surgery on the tissue response
(2018-02-14)
This research project focuses on the multiple challenges associated with implants that breach the skin. The role of device design, host site, and surgical approach on tissue response and outcome are evaluated, experimentally ...