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Epidemiologic studies on human enteric viruses in Cameroon
(2013-11-27)
Enteric viruses are a diverse group of viruses that include those that multiply in the intestinal epithelium and cause gastroenteritis, and those that first multiply in the intestine and then spread to extra-intestinal ...
Surgical Management of Rib Fractures Following Trauma
(2019-04-08)
Background: Surgical management of chest wall injuries has received increasing attention in recent years. The aim of this thesis was to study the mechanism of injury
(MOI) in relation to chest wall injury patterns and ...
Assessment of excess skin and outcome of body contouring surgery in post bariatric patients
(2014-12-08)
Aim: A negative effect of massive weight loss is the development of excess skin. Excess skin causes both physical and psychological problems for those affected and their families. The overall aim of this thesis was to ...
Early stage inflammation and cancer as reflected in the gastrointestinal mucus composition: implications for diagnosis, prognosis and pathogenesis
(2018-10-23)
Mucus covers our inner interfaces towards the environment, providing protection while enabling vital interaction with the outside world. The mucus is built around mucin proteins, which are important for our defences against ...
Targeted radiotherapy in metastatic neuroendocrine tumours: clinical and experimental studies
(2018-11-06)
ABSTRACT
Neuroendocrine tumours (NET) often present at a metastatic stage, which diminishes the possibility for curative surgery. Peptide receptor radiotherapy (PRRT) with 177Lu-DOTATATE targets somatostatin receptors, ...
The regulatory role of osteoblasts in castration-resistant growth of prostate cancer
(2015-08-18)
Bone metastasis of a predominantly osteoblastic (sclerotic) nature is the outcome for the vast majority of patients with castration-resistant prostate cancer (CRPC). Pathologically, osteoblastic tumors are characterized ...
Children with spina bifida and their mothers in Palestine. Lived experiences, self perceived health and sense of coherence
(2019-03-20)
ABSTRACT
The overall aim in this thesis was to describe the lived experiences of children with spina bifida (SB) and their mothers while living under specific social and cultural conditions in West Bank, Palestine. A ...
Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency
(2012-10-10)
The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with ...
Methylome and Transcriptome Profiling of Hepatocytes Derived from Human Pluripotent Stem Cells
(2018-02-22)
Six hundred million people suffering from liver diseases worldwide of which the lethality is two million. Freshly isolated hepatocytes from the liver have been used for transplantation purposes and are extensively used to ...