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Influence of inflammation and of stage of lung development on the development of neonatal lung injury
(2010-11-26)
Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological ...
Surgery and Ischemia in Uterus Transplantation. Studies in various experimental models.
(2007-09-10)
The use of transplantation to enhance quality of life is a growing clinical field that also includes transplantation of reproductive organs. Transplantation of the uterus has been suggested as future method to treat uterus ...
Regulation of IL-6-signaling and inflammatory response – Role of insulin, FOXO1 and PKCδ
(2010-04-27)
The aim of this thesis was to investigate if and how insulin antagonizes interleukin-6 (IL-6)-signaling and
action using both 3T3-L1 mouse adipocytes (Paper I) and HepG2 human hepatocytes (Paper III). We also
investigated ...
Cyclooxygenase activity and tumor progression
(2008-09-26)
Invasive growth of malignant tumors is associated with local and systemic inflammation, which may promote progression and metastases. Inflammation is also responsible for appearing manifestations of advanced cancer as ...
Cardiovascular structure and function in obesity. The impact of body composition, sleep apnea and sustained weight loss
(2012-10-23)
Background: Obesity is associated with disturbances in cardiovascular structure and function varying along with the degree of fatness, but the mechanisms underlying this co-variation are unclear. Short-term weight loss ...
Studies on the atherogenicity of apoB-containing lipoproteins in type 2 diabetes
(2009-01-15)
Type 2 diabetes (T2D) and the metabolic syndrome (MetS), two conditions that are rapidly increasing in prevalence, as well as the dyslipoproteinemia and subclinical inflammation characteristic for these conditions, are ...
Muscarinic receptors in the urinary bladder - The role of the urothelium regarding cholinergic and nitrergic effects in inflammation
(2010-11-19)
Inflammation alters the functional properties of the urinary bladder. Interstitial cystitis (IC) is a chronic inflammatory syndrome in man that is characterized by urgency, frequency and visceral pain. The overall aim of ...
The role of S100A4 protein as a regulator of inflammation and bone metabolism in experimental arthritis
(2011-10-28)
S100A4 belongs to the family of calcium-binding S100 proteins and modulates cell proliferation,
cytoskeletal rearrangement, cell motility, and angiogenesis. Increased levels of S100A4 expression
correlate with high ...
Functional and Phenotypic Studies of Eosinophilic Granulocytes in Patients with Eosinophilic Esophagitis
(2015-04-27)
Eosinophilic Esophagitis (EoE) is a chronic inflammatory disorder of unknown etiology, in which the esophagus is infiltrated by eosinophils and T cells. Topical corticosteroids are one of the treatment options for patients ...
149. Diesel Engine Exhaust
(Arbets- och miljömedicin vid Göteborgs universitet & Arbetsmiljöverket, 2016-06-08)
Diesel engine exhaust is a complex mixture of gaseous and particulate compounds produced during the combustion of diesel fuels. The gas phase includes carbon dioxide, nitrogen oxides (NOX), carbon monoxide and small amounts ...