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Femoroacetabular impingement syndrome. Trends and outcomes after arthroscopic treatment in the general and athlete population
(2021-08-18)
Femoroacetabular impingement syndrome (FAIS) is a common cause of hip pain in the young and athletic population. The diagnosis - FAIS - is based on a triad of symptoms, clinical evaluation and radiographic signs. The ...
Metabolic alterations and adipose tissue dysfunction in individuals with a family history of type 2 diabetes
(2022-02-08)
ABSTRACT
Aims
The overall aim of this doctoral thesis was to further examine the anthropometric, metabolic and adipose tissue dysfunctions, as well as explore novel metabolites, associated with type 2 diabetes mellitus ...
Assessment of neurological prognosis after cardiac arrest – clinical and neurophysiological aspects
(2021-04-06)
Background: Post-resuscitation care after cardiac arrest in adults includes targeted temperature management (TTM) to mitigate secondary brain injury. The recommended target temperature is between 32°C and 36°C after a ...
Translational and clinical aspects of pancreatic cancer
(2021-05-10)
Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative ...
Price sensitivity and regional variation in health care
(2021-02-12)
Understanding the consequences of current health policy is important in order to design and develop a health care system suitable for future challenges. The purpose of this thesis is to bring evidence on the determinants ...
Human iPSC-derived neuronal networks. Development and application for compound evaluation
(2022-02-03)
Research on human brain development and function in health and disease has been hampered by limited access to primary human tissue and limited translatability of animal studies. This knowledge gap is encouraging the use ...
On tissue engineering of pig, human, and non-human primate tissues
(2020-05-07)
Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes ...
The roles of osteoclasts and RUNX2 in the progression of prostate cancer bone metastases
(2021-11-23)
Metastasis to the skeleton is the major cause of death from prostate cancer (PC). Patients with metastatic PC are treated with androgen deprivation therapy (ADT) to decrease testosterone levels and thereby inhibit further ...
The role of glycoproteins in glomerular pathophysiology
(2021-09-01)
Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no ...
Treatments and outcomes in bipolar disorder
(2020-11-02)
Bipolar disorder is defined by recurring mood episodes and patients
have a markedly increased risk of suicide. Pharmacological and psychological
treatments for bipolar disorder have proven efficacy in clinical
trials ...