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Now showing items 21-30 of 149
Obesity, weight reduction treatment and IVF
(2021-10-26)
Background: Obesity is a growing problem on a global scale and women with obesity have a higher risk for infertility and complications, for both mother and child, in pregnancy and birth. This has been shown both regarding ...
The role of wastewater in surveillance and emergence of antibiotic resistant bacteria
(2021-05-25)
As antibiotic resistance spreads among bacterial pathogens, it reduces treatment
options and increases treatment failures of infectious diseases. Strategies
employed to reduce this spread or adapt to its consequences ...
Body weight, body size and early cardiovascular disease. Epidemiological studies using Swedish registries
(2021-05-04)
Background: Obesity is a known risk factor for cardiovascular morbidity and mortality, as well as for atrial fibrillation and heart failure. While overweight and obesity have become increasingly more common in Sweden and ...
Cerebrospinal fluid biomarkers and cognition in older adults
(2021-04-21)
Alzheimer’s disease (AD) is the most common type of dementia. The cause of the disease is unknown, but a substantial amount of evidence suggest that the disease is started by an imbalance in the production and clearance ...
Enriched, task specific therapy in the chronic phase after stroke
(2021-03-29)
Recovery and improvement of motor functions and abilities after stroke depend on the spontaneous recovery process but also on the reorganization of neural mechanisms. In animal studies, an Enriched Environment (EE) has ...
Fluid biomarkers of extracellular matrix remodelling across neurological diseases
(2021-02-12)
Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. This has placed a ...
On the efficacy and prescription of serotonin reuptake inhibitors
(2021-09-09)
This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic ...
Rectal Cancer and Quality of Life. Aspects on Communication and Patient Education
(2021-03-16)
Background This thesis reports the results of three studies based on a pro-spective cohort study of an unselected population of patients with rectal cancer, and one study based on an exploratory study of a new patient ...
The role of MBOAT7 on fatty liver disease
(2021-02-18)
Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. ...
Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C. elegans
(2021-10-29)
Cancer is a major cause of mortality throughout the world. Despite the effort of the scientific community, plenty remains to understand about the biology or genetics of cancer. In solid tumors often as many as 90-99% of ...