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Ge alla en chans att vara med - Brukarinvolvering i forskning med och för sköra äldre personer
(2021)
Aims: The overall aim with this thesis was to explore how the voices of frail older people can be heard and acknowledged through user involvement in research on aging and health. Two studies are included with the specific ...
Cervical and vaginal cancer - aspects on risk factors, prevention and treatment
(2021-03-26)
Background: Participation in screening is associated with a major risk reduction in cervical cancer, but there is a lack of knowledge on whether the cost to the individual has an effect on the participation rate. Women ...
Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery
(2020-05-15)
Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal ...
Polycystic ovary syndrome in a lifetime perspective
(2020-12-08)
Background: Polycystic ovary syndrome (PCOS) is common, affecting 9-18% of women. PCOS is associated with symptoms due to hyperandrogenism and ovarian dysfunction, but is also associated with the metabolic syndrome including ...
Novel biomarkers associated with histotype and clinical outcome in early-stage ovarian carcinoma
(2020-04-15)
Ovarian cancer is a collective name for multiple malignancies deriving from or involving the ovary, mainly comprising five histotypes of epithelial origin (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), ...
Appetite-regulating peptides and natural rewards: emphasis on ghrelin and glucagon-like peptide-1
(2020-09-02)
Evolutionary conserved natural behaviors, such as foraging and sexual
behaviors, are strongly associated with reward processes. Brain areas
important for reward processes include, but are not limited to, the nucleus
accumbens ...
Recurrent infection with Extended-Spectrum Beta-Lactamase (ESBL) -producing Enterobacteriaceae
(2020-05-05)
Infections with Extended-Spectrum Beta-Lactamase (ESBL)-producing Enterobacteriaceae (EPE) are increasing globally. The most common EPE are the gut pathogens Escherichia coli (ESBL-E. coli) and Klebsiella pneumoniae (ESBL-K. ...
Physiological roles of amyloid precursor protein in vivo - zebrafish as a model
(2021-10-26)
Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). APP ...
Patient safety during intrahospital transports in intensive care. Hazards, experiences and future measurements
(2020-04-16)
Patient safety is an attribute of the healthcare system that minimizes the incidence of adverse events (AEs), and that entails identifying the causes of harm and preventive strategies. Intrahospital transport (IHT) of ...
Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries
(2022-02-10)
Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can ...