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Now showing items 2591-2600 of 2844
Rhinosinusitis beyond the upper airways. Epidemiological aspects.
(2023-05-09)
Rhinosinusitis (RS) is a prevalent, multi-factorial disease, including several subgroups of disease with different characteristics and pathophysiology. RS symptoms for more than 12 weeks are defined as chronic rhinosinusitis ...
Genomic signatures in viruses
(2023-05-25)
In an age of global pandemics, studying how viruses and their genomes evolve is of great importance. It has previously been found that the genomes of many eukaryotes and prokaryotes have specific preferences for nucleotides, ...
On the biological response to different biomaterials under normal and irradiated conditions
(2022-03-10)
There are several challenges when introducing an implant into a host. Concerning soft tissues, major complications are fibrosis and capsule contracture, whereas for bone, failure of osseointegration may occur. In addition ...
NOTUM and RSPO3 in Bone - WNT signaling modulators regulating the skeleton
(2023-05-02)
Osteoporosis is a skeletal disease affecting millions of people worldwide, often leading to fragility fractures and a decreased quality of life. There is an unmet medical need for new anabolic, bone building, treatments. ...
Left ventricular dysfunction in critically ill patients
(2023-09-08)
ABSTRACT
Background: Cardiac dysfunction is common in Intensive Care Unit (ICU)
patients and can contribute to multiorgan failure and death. Despite this, few
studies have been performed on pathogenies, prevalence, ...
lnnovating eldercare. Exploring older adults' peer-to-peer practices in the outskirts of public care
(2022-03-03)
The focus of this thesis is everyday care between older adults and their peers who are not family. Public eldercare is also discussed. At first glance, these two issues may seem quite different. Nevertheless, trends in ...
Pre/Peri/Earl-Life Exposures and Early Child Neurodevelopment: Results from the Japan Environment and Children's Study (JECS)
(2023-08-18)
Background: Combinations of genetic and environmental factors contribute to aetiologies of neuropsychiatric problems and neurodevelopmental disorders (NDDs) in intricate manners. Among the environmental factors, exposures ...
Thymus dysfunction in the 22q11 deletion syndrome
(2023-04-12)
Introduction: The 22q11.2 deletion syndrome (22q11DS) is associated with heterogeneous clinical findings, including T-cell immunodeficiency resulting from thymus hypoplasia. Newborn screening programs based on the ...
Cerebrospinal fluid studies of bipolar disorder
(2022-04-14)
The pathophysiology of bipolar disorder remains to be elucidated. One approach to studying brain processes is analysis of cerebrospinal fluid (CSF). This thesis comprises five studies based on the Sankt Göran Bipolar Project ...