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Now showing items 2561-2570 of 2594
lntestinal health after pelvic radiotherapy - towards understanding persisting pathophysiological mechanisms
Pelvic cancer survivors struggle with life-long symptoms caused by radiotherapy. Many pelvic cancer survivors live with a constant fear of leaking faeces and the need to always have a toilet within reach. Some of these ...
Neutrophil Serine Proteases in Health and Disease
Neutrophils are filled with many antimicrobial agents, including the neutrophil serine proteases (NSPs); a group of proteases including Elastase, Proteinase 3, and Cathepsin G. Synthesized as inactive proforms, the NSPs ...
Supporting mental health - Effects, communicative processes and experiences of a person-centred eHealth intervention
Corresponding to the appeal to develop supportive strategies for people on sick leave with common mental disorders (CMDs), focusing beyond illness and towards mental health, this thesis evaluates an eHealth intervention ...
Molecular and structural studies of proteins required for mitochondrial DNA maintenance
Mitochondria are membrane-bound organelles that produce the majority of ATP used to drive metabolic processes in eukaryotic cells. A unique feature of mitochondria is the existence of a separate mitochondrial DNA (mtDNA), ...
Proximal and distal humeral fractures. Outcome of primary arthroplasty
This thesis deals with both proximal humeral fractures and elbow injuries, especially distal humeral fractures. The main focus is difficult fractures in the elderly. Few randomized controlled trials (RCTs) are available. ...
Allergic and non-allergic asthma: Translational research in immunology
Asthma is a chronic heterogeneous respiratory disease affecting more than 300 million people globally. The different phenotypes, including allergic and nonallergic asthma, are driven by different underlying mechanisms ...
Occupational heat exposure and kidney disease - Studies on the role of heat stress in the Mesoamerican epidemic of Chronic Kidney Disease of non-traditional origin
This thesis examines the association between heat stress and kidney disease in Mesoamerica using different perspectives and methods. An ecologic study found that hot, sugarcane-cultivating regions had elevated chronic ...
Exploring small airways using breath analyses
Background: Airway irritants such as allergens, tobacco smoke and viruses may cause damage in the small airways, usually undetected with routine diagnostic methods. Analyses of endogenously produced nitric oxide (NO) and ...
Nutritional impact on health in patients with Rheumatoid Arthritis
Objective:
Rheumatoid Arthritis (RA) is the most common autoimmune rheumatic disease, affecting around 0.5-1% of the population. The aim of this thesis was to study dietary impact on markers of health in patients with ...
To give birth in late- and post-term pregnancy - women's experiences and perspectives
Childbirth is a lifechanging event, and women carry with them the experience throughout life. Around one in five pregnancies reach gestational week 41. When to recommend induction of labour for those extending 41 gestational ...