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Now showing items 11-20 of 22
Weight loss studies in obese patients. Aspects of very-low-energy diet treatment and effects of obesity surgery on disability pension
(2010-03-02)
Obesity is associated with increased risk of serious medical conditions, impaired quality of life, reduced working capacity, and shortened life expectancy. Obesity surgery is the most effective weight loss treatment with ...
IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice
(2016-01-29)
It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ...
Regulation of IL-6-signaling and inflammatory response – Role of insulin, FOXO1 and PKCδ
(2010-04-27)
The aim of this thesis was to investigate if and how insulin antagonizes interleukin-6 (IL-6)-signaling and
action using both 3T3-L1 mouse adipocytes (Paper I) and HepG2 human hepatocytes (Paper III). We also
investigated ...
Urethral strictures in men: Studies on reconstructive surgery and pathophysiology
(2016-11-14)
Urethral stricture is a common disease that is characterised by fibrotic tissue arising from inflammation after urethral injury. Urination is inhibited when there is total obstruction, and the suffering is immense. Following ...
Bone and fat tissue in children and adolescents: studies with focus on osteocalcin
(2016-09-15)
The general AIM was to investigate the possible interplay between bone and
fat tissue through clinical studies of children and adolescents. Osteocalcin
(OC), a bone formation marker, has been proposed to act as a link ...
Aspects of Plasminiogen Activator Inhibitor 1 in Metabolic Syndrome
(2016-05-31)
Plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system
and binds irreversibly to tissue-type plasminogen activator (t-PA), and thereby inhibits the protective action of t-PA against ...
Intestinal adaption in response to Roux-en-Y gastric bypass surgery
(2015-11-12)
ABSTRACT
Background: Obesity is a condition with increasing prevalence that leads to morbidity, decreased quality of life and reduced life expectancy. The only effective evidence-based treatment is bariatric surgery. The ...
Studies on the Associations between Dental Caries, Periodontal Disease and Different Systemic Conditions
(2012-04-19)
Background and aims: Dental caries and periodontal disease are the two most common oral diseases in man. Evidence shows that they may be directly or indirectly related to each other and to other systemic conditions. The ...
Surveillance of childhood obesity in Sweden. Focus on lifestyles and socioeconomic conditions.
(2014-09-05)
Background and aim: There is a general lack of childhood obesity surveillance systems throughout Europe, including Sweden. Such systems are needed to develop policies, evaluate interventions and track secular changes in ...
Childhood overweight and obesity in preschool children - an emerging problem in urban and rural Vietnam. A study of epidemiology and associated factors.
(2017-03-10)
Background: Childhood overweight and obesity is considered a global epidemic. From being a health problem mainly in high-income countries, it is now an emerging problem in low- and middle-income parts of the world as well. ...