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Now showing items 11-20 of 141
Early detection of ESSENCE in Japanese 0-4-year-olds. Studies of neurodevelopmental problems in the community and in clinics
(2018-02-14)
BACKGROUND: Early identification of children with neurodevelopmental problems/ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) is a critical issue both in the community and in clinical ...
Genetic studies of the regulation of bone parameters and serum testosterone
(2018-05-29)
Osteoporosis is a common disease characterized by low bone mass and microarchitectural deterioration of bone tissue leading to increased risk of fracture and represents a huge economic burden on health care systems. The ...
Intravoxel incoherent motion modeling - Optimization of acquisition, analysis and tumor tissue characterization
(2018-09-13)
Intravoxel incoherent motion (IVIM) analysis provides a means to obtain information on diffusion and perfusion from a single MRI sequence. The measurements are completely noninvasive and the results have been shown to be ...
Colonic mucus structure and processing
(2018-10-05)
The mucus layer covering the colonic epithelium creates a crucial first line of defense against the gut residing bacteria. Several lines of evidence suggest that a functional mucus layer is essential for health. For example, ...
Androgen receptor signaling mechanisms in bone
(2018-12-13)
Osteoporosis is a common age-related disease that increases the risk of fractures. Androgens are crucial for bone health in males. Although a substantial part of the effects of androgens on the skeleton is mediated via ...
Host-Virus Interactions in Asthma and COPD
(2018-10-26)
Asthma and chronic obstructive pulmonary disease (COPD) are associated with periods of worsened symptoms, known as exacerbations. Severe exac-erbations can result in hospitalisation, irreversible decline of the disease and ...
Women's and Men's Health care utilisation from a cost perspective
(2018-10-23)
The aim of this thesis was to explore sex differences in health care utilisation and costs (i) in a region in Sweden, (ii) in treatment of dialysis patients across the region, and (iii) in the treatment of specified ...
Immunotherapy and immunosuppression in myeloid leukemia
(2018-11-12)
Acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis ...
Adult Chiari I malformation - Clinical presentation and surgical outcomes
(2018-04-04)
Background
Chiari I malformations (CMIs) are hindbrain anomalies that are characterized by cerebellar tonsillar ectopia. The typical presentation is an occipital headache that worsens with exertion. In this thesis, I focus ...
Natural History of Human Papillomavirus Infections and Other Sexually Transmitted Infections in Rwanda-Immunological Aspects of the Uterine Cervix
(2018-11-23)
Objective: Cervical cancer stands for the predominant cause of cancer death among Rwandan women. Chronic Human Papillomavirus (HPV) infection constitutes the main risk factor. We here assessed the prevalence and incidence ...