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Now showing items 11-20 of 132
Studies on new pharmacological treatments for alcohol dependence - and the importance of objective markers of alcohol consumption
(2016-05-26)
This thesis will guide you through three randomized controlled trials (RCT) on three pharmacotherapies for alcohol dependence; the antidepressant drug mirtazapine, the smoking cessation drug varenicline and the glycine-uptake ...
Epidemiological Aspects of Renal Impairment in Patients with Type 2 Diabetes
(2016-05-04)
Diabetes is a leading cause of renal impairment (RI) and indication of the need for renal replacement therapy in many parts of the world. Albuminuria and RI are the two main forms of diabetic kidney disease. The overall ...
The role of neonatal immunity in preterm brain injury
(2016-11-23)
Perinatal brain injury is an important cause of mortality and morbidity and is associated with neurological disabilities such as those seen in cerebral palsy. Prematurity, especially in combination with very low birth ...
Whole Genome Sequencing of Enterotoxigenic Escherichia coli
(2016-05-06)
Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of diarrhea but little is known about the evolution and genomic composition of ETEC. The main aim of this thesis was to generate a large collection of ...
Gastrointestinal Symtoms and Fatigue in Patients with Quiescent Ulcerative Colitis
(2016-11-10)
Gastrointestinal symptoms compatible with Irritable Bowel Syndrome (IBS) and fatigue are common in patients with quiescent ulcerative colitis (UC). The causes of these symptoms remain to be clarified. The overall aim of ...
The Role of Insulin and Insulin-like Ischemic Stroke and Cognitive Impairment
(2016-11-02)
Background and aims: Insulin, insulin-like growth factor-I (IGF-I), and the six high-affinity IGF-binding proteins (IGFBPs) play an important role in growth, metabolism and regeneration throughout the entire life span. In ...
Membranous Nephropathy - Challenges in diagnostics and treatment
(2016-04-04)
The variability in the pathogenesis, clinical presentation and outcome of membranous nephropathy (MN) poses major clinical challenges and raises different questions, both regarding diagnostics and treatment of patients ...
Development of targeted alpha therapy with Bi-213 and At-211 for the treatment of disseminated cancer
(2016-03-01)
Radioimmunotherapy (RIT) is a type of targeted cancer therapy. The concept behind RIT is to deliver cytotoxic ionizing radiation to tumor cells by attaching radionuclides to tumor-specific antibodies. The radioimmunoconjugates ...
Cardiovascular and pulmonary health effects of air pollution - long term effects in Sweden and effects of wood smoke
(2016-02-24)
Exposure to air pollution is associated with increased morbidity and mortality
in cardiovascular and pulmonary diseases. Main suggested mechanisms are
airway and systemic inflammation, affecting hemostasis in the short ...
Se och hör mig. Personer med förvärvad dövblindhets erfarenheter av delaktighet, rehabilitering och medborgerligt liv
(2016-12-20)
Introduction and objective: There are very few research studies about the experiences of
living with deaf blindness. The objective of this dissertation is to capture the experiences of
people with acquired deafblindness ...