The Wnt signaling pathway plays a central role in bone and cartilage embryonic development, processes that are recapitulated during regeneration. Imbalance in such well conserved and complex system often contributes to ...

Syfte Det övergripande syftet med avhandlingen var att definiera och beskriva självbestämmande i relation till sköra äldre personer, instrumentutvärdering för att skatta äldre personers självbestämmande samt utvärdera ...

The overall aim of this thesis was to evaluate the effects of health-promoting and disease-preventive interventions on health and frailty in very old community-dwelling persons, and to explore the participants’ experiences ...

Renal cancer causes over 100,000 annual deaths worldwide, and the incidence is increasing. Clear cell renal cell carcinomas (CCRCC), constituting 75% of renal cancer, are known for their high metastatic frequency and ...

The general aim of this thesis was to explore the associations between sex hormones and high blood pressure in men and women and to investigate their further role in the development of acute myocardial infarction particularly ...

Frail older persons are often dependent on care and support from several different care providers, including hospital and primary health care as well as municipal health and social care. The increasing complexity of care ...

Cataract is an opacification of the eye lens, constituting the major cause of blindness globally. Oxidative stress is a key factor in the formation of cataract and female gender is a known risk factor for age-related ...

Chronic liver disease is a major health burden worldwide. Major determinants of this condition are viral infections, alcohol abuse and obesity. Genetic background modulates the effect of damaging agents on the liver. The ...

The radiohalogens 123I, 124I, 125I, 131I, and 211At are routinely used or proposed for diagnostic and therapeutic purposes. The different characteristics and application areas of these radioiodine isotopes, together with ...