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Developing brain and systemic inflammation: a "Toll-like" link with consequences
(2017-05-24)
The developing brain is vulnerable to external insults, and perinatal brain injury (PBI) is a major cause of life-long neurological syndromes such as cerebral palsy. Currently, no pharmaceutical intervention is available. ...
Antimicrobial peptides in the treatment of infectious and inflammatory conditions - Preclinical studies of mechanism of action, efficacy, and safety
(2016-10-20)
The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious ...
Progression and treatment of experimental peri-implantitis
(2011-04-21)
Peri-implantitis is characterized by inflammatory lesions in peri-implant tissues and loss of supporting bone. The aims of the present series of studies were to analyze (i) spontaneous progression and (ii) the effect of ...
The percutaneous implant. The effects of design, host site and surgery on the tissue response
(2018-02-14)
This research project focuses on the multiple challenges associated with implants that breach the skin. The role of device design, host site, and surgical approach on tissue response and outcome are evaluated, experimentally ...