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Molecular Monitoring of Chronic Myeloid Leukemia Treated with Imatinib Mesylate
(2007-08-15)
The BCR-ABL fusion gene product is a constitutively activated tyrosine kinase, which is fundamental in the pathogenesis of chronic myeloid leukemia (CML). Imatinib mesylate (imatinib, Glivec® or Gleevec®), a small molecule ...