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Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)
Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ...
The effect of intra-abdominal local anaesthetics following major gynaecological surgery. Clinical and experimental studies
(2020-05-18)
Background: Local anaesthetics (LA), in addition to inhibition of pain signalling, also have anti-inflammatory
properties. In vitro studies have demonstrated anti-proliferative and cytotoxic effect of
LAs on cancer cells ...
On HIV in the elderly and vitamin B metabolism in HIV infection
(2022-01-17)
The evolution of the human deficiency virus (HIV) field is unparalleled in the history of infectious diseases. From the first cases in the beginning of the 1980s, when an HIV diagnosis was a death sentence, through the ...
Epithelial signatures in respiratory disease
(2021-11-25)
The epithelium of the human airways protects us against harm and helps
maintain immune homeostasis. In respiratory diseases such as asthma and
COPD, the functions of the epithelium are altered and can cause or contribute
to ...
The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury
(2022-01-13)
The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common ...
Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery
(2020-05-15)
Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal ...