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Gut bacteria, regulatory T cells and allergic sensitization in early childhood
The hygiene hypothesis postulates that reduced or altered microbial exposure early in life may lead to impaired immune maturation and, as consequence of this, development of allergic disorders. Thus, we examined if the ...
CC16 in allergy and allergic inflammation
Clara cell 16-kDa (CC16) is an anti-inflammatory protein mainly produced in the lung epithelium by Clara cells. Patients with asthma have lower levels of CC16 in bronchoalveolar lavage fluid and serum compared with healthy ...