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Intravoxel incoherent motion modeling - Optimization of acquisition, analysis and tumor tissue characterization
(2018-09-13)
Intravoxel incoherent motion (IVIM) analysis provides a means to obtain information on diffusion and perfusion from a single MRI sequence. The measurements are completely noninvasive and the results have been shown to be ...
Targeting NOX2 in cancer
(2018-02-27)
Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a ...
Identification and early detection of cancer patients in primary care
(2018-03-21)
Aim The aim of this thesis was to investigate how general practitioners (GP) can identify patients in primary care with potential common cancers, at an early stage. It was also to design a risk assessment tool for colorectal ...