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Mucus and mucins during gastrointestinal infections
The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate ...
Study of the colonic mucus layer by mass spectrometry
The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the ...
Helicobacter spp. interactions with mucins: adhesion and mucin regulation of pathogen proliferation and gene expression
Helicobacter pylori colonizes the gastric mucosa of approximately half of the world’s population and is a risk factor for gastritis, peptic ulcers and gastric cancer. H. pylori is surrounded by, and adheres to, the heavily ...