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Pathophysiological impact of targeting the ROS-p53 axis
The goal of this PhD thesis was to define the importance of the interplay between reactive oxygen species (ROS) and their activation of the tumor suppressor p53 in development and disease. We addressed this question using ...
Biological relevance and prognostic significance of radial artery intima-media thickness
Cardiovascular disease (CVD) is the major cause of death both in Sweden and globally. Atherosclerotic vascular changes are considered the major underlying pathology leading to clinical manifestations of CVD, e.g. myocardial ...