Now showing items 1-5 of 5
Astrocyte-mediated short-term synaptic depression
Short-term synaptic plasticity, the activity-dependent regulation of synaptic efficacy that occurs in the timeframe of milliseconds to seconds, is a fundamental property of the synapse, mostly attributed to changes in ...
Inflammation and behavior following irradiation-induced injury in the developing brain
Radiotherapy is used in the treatment of pediatric brain tumors and is often associated with debilitating late effects, such as intellectual impairment. Areas in the brain harboring stem cells are particularly sensitive ...
Gastric Inhibitory Polypeptide in the brain
The hippocampus is an area of active cell proliferation and neurogenesis within the adult mammalian brain. Adult neurogenesis is of great importance for the brain, since it increases neuroplasticity and the ability to ...
GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function
Abstract Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments ...
Regulation of postnatal neurogenesis and brain angiogenesis by thyroid hormone
Thyroid hormone (TH), which is secreted by the thyroid gland, exerts significant effects on the central nervous system (CNS), especially during development, so that delayed treatment of perinatal hypothyroidism results ...