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Analysis of Binding Events and Diffusion in Living Cells
It is well known that diffusion is the main mode of transport in living cells, but the consequences of diffusion in a complex cellular environment are not generally appreciated. In this thesis, we have investigated several ...
Functional characterization of the secretory pathway and the role of COPI vesicles
In the secretory pathway, proteins synthesized in the endoplasmatic reticulum move through the Golgi apparatus in a cis-to-trans direction and then sorts into different types of vesicles at the trans-Golgi network. How ...