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Biological mass spectrometry. Development of methods for protein and peptide analysis applied in neuroscience


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Title: Biological mass spectrometry. Development of methods for protein and peptide analysis applied in neuroscience
Authors: Gobom, Johan 1970-
Issue Date: 1999
University: Göteborgs universitet/University of Gothenburg
Institution: Department of Psychiatry and Neurochemistry
Avdelningen för psykiatri och neurokemi
Date of Defence: 1999-12-08
Publication type: Doctoral thesis
Keywords: proteins
peptides
neuropeptides
brain
matrix-assisted laser desorption/ionization mass spectrometry
Abstract: This thesis describes the development and use of biological mass spectrometry for protein and peptide analysis, and its application in neuroscience. Emphasis is placed on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF-MS), which has been the technique primarily used in the studies. Aspects relevant to the mass spectrometric study of proteins and peptides in neuroscience include the ability to purify and perform enzymatic or chemical reactions on small amo... more
URI: http://hdl.handle.net/2077/11196
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

 

 

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