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Cardiovascular and metabolic control in obese children and adolescents
(2008)
Childhood obesity is an emerging risk factor for disease and mortality worldwide. Thecardiovascular consequences and prevention thereof need to be further investigated. Exerciseand weight loss are well examined and effective ...
The complement system in stherosclerosis and arthritis
(2004)
The complement system plays an essential role in the humoral immune response. Activated complement has diverse functions, including the initiation of inflammation, recruitment of leukocytes, clearance of immune complexes, ...
Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice
(2004)
Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development ...
The role of PPARalpha and growth hormone in hepatic lipid metaboism and atherosclerosis
(2006)
Dyslipidemia mainly results from oversecretion of apoB-containing lipoproteins from theliver and is one of the most important risk factors for the development of atherosclerosis.Growth hormone (GH) plays a key role in the ...
Proteoglycans, group IIA phospholipase A2, and lipoproteins.Potential involvement in atherogenesis
(2000)
Atherosclerosis is a multifactorial complex disease characterized by a focal accumulation of ApoB-100 containing lipoproteins, extracellular matrix (ECM), and cells in the arterial intima accompanied by an inflammatory ...
Imaging of subclinical atherosclerosis by B-mode ultrasound. Measurement reproducibility and assessment of atherosclerotic plaque occurrence, size and echogenicity in relation to cardiovascular disease
(2004)
Atherosclerosis is an insidious disease that in general has a very long clinical silent phase. This disease does not take place uniformly in the arterial tree, instead major sites for this disease process are the coronary ...
Atherogenic lipoproteins and their interaction with proteoglycans
(2003)
Atherosclerosis is a multi-factorial disease and its pathogenesis is still unclear. However, accumulating evidence during recent years has led to the concept that subendothelial retention of atherogenic lipoproteins is ...
Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis
(2002)
The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate ...
Lipoprotein(a) in cardiovascular disease
(2002)
The atherosclerotic process is continuous and starts early in life. Risk factors for atherosclerosis include hyperlipidemia, hypertension, smoking and diabetes mellitus. Fatty streaks characterised by lipid-laden ...