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Cardiovascular, behavioural and metabolic consequences of growth hormone overexpression in transgenic mice
Growth hormone (GH) exerts major effects on body growth and metabolism. GH is also important in controlling cardiovascular function and behaviour. To study the role of growth hormone in cardiovascular function and regulation ...
Odontoblast phosphate and calcium transport in dentinogenesis
It has been suggested that odontoblasts are instrumental in translocating Ca2+ and inorganic phosphate (Pi) ions during the mineralization of dentin. The aim of this thesis was, therefore, to study the expression of ...
Studies on health-related quality of life in patients with chronic obstructive pulmonary disease
Aims. To describe health-related quality of life (HRQL) in chronic obstructive pulmonary disease (COPD), to develop a Swedish version of the St George's Respiratory Questionnaire (SGRQ), to study factors related to HRQL ...
Physical performance, pain and pool exercise in individuals with late effects of polio
The overall purpose of the studies was to obtain knowledge about physical performance and related factors in individuals with late effects of polio. The specific aims were to provide a description of pain and how it is ...
Effects of growth hormone on cardiovascular risk factors and atherosclerosis
Hypopituitary patients with growth hormone (GH) deficiency (GHD) have increasedmorbidity and mortality from cardiovascular disease (CVD). GH treatment has both beneficialand potentially negative cardiovascular effects. The ...
Immunobiochemical mechanisms and pathophysiological significance of β₁-adrenergic receptor autoantibodies in dilated cardiomyopathy
Idiopathic dilated cardiomyopathy (IDC) is a heart muscle disease of unknown origin and the second most common reason for heart transplantation. Autoimmune processes are involved in the progression of the disease. Circulating ...