It is increasingly recognised that asthma and cystic fibrosis (CF) frequently involves the peripheral airways. Characteristic features of abnormal peripheral airway function are uneven ventilation distribution and increased ...

The incidence of allergic diseases is increasing in the industrialized countries. Epidemiological studies indicate that there is an association between exposure to high levels of endotoxin or cat allergen during infancy ...

Inflammatory bowel disease (IBD) is characterized by chronic and relapsing intestinal inflammation of unknown etiology, but immune activation by the commensal microbiota probably plays a major role. The two major categories ...

Background/aims: Narcolepsy is a lifelong sleep disorder with an onset most frequently in the second decade of life. The cardinal symptoms are excessive daytime sleepiness, cataplexy, hypnagogic and hypnopompic hallucinations ...