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Blood pressure, blood pressure development and potential risk factors for hypertension with special reference to metabolic factors and kidney function
(2002)
Objectives: The overall aim of this thesis was to search for predictors of blood pressure development with special reference to anthropometric, metabolic and renal function variables.Study populations and methods: Two large ...
Autonomic function and myocardial repolarisation. Studies in renal diseases and in spinal cord injury
(2003)
Both experimental and clinical evidence indicates that cardiac parasympathetic markers such as baroreflex sensitivity (BRS) and heart rate variability (HRV) have significant prognostic value. Furthermore, increased myocardial ...
Renal denervation in patients with resistant hypertension
(2018-02-05)
BACKGROUND
Catheter-based renal denervation (RDN) is a potential modality in the treatment of patients with resistant hypertension (RH). The biological effects of RDN are not fully comprehended and studies examining its ...
Local regulation of the endogenous fibrinolytic system in man
(2001)
The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (tPA). The endothelium synthesises and stores tPA and regulated release of the enzyme is an important mechanism ...
Angiotensin II and vascular disease. Studies in rats and atherosclerosis-prone mice
(2006)
Angiotensin II (Ang II) is of importance for a number of physiological processes but also plays an important pathophysiological role in cardiovascular disease. The aim of this thesis was to evaluate the role of Ang II in ...
Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers
(2013-11-11)
Research questions:
1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)?
2 How does myocardial ischemia affect ...
Sleep disordered breathing and hemodynamic function
(2001)
This thesis addresses the association between sleep disordered breathing (SDB) and hemodynamic function. A cross sectional study in a sleep laboratory cohort (n=1190) demonstrated a dose-response relationship between the ...
Impairment of Endothelial Thromboprotective Function by Haemodynamic and Inflammatory Stress - Implications for hypertensive disease
(2007-06-29)
The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA). The endothelium synthesizes and stores t-PA and regulated release of the enzyme is an important local ...
Alzheimer's disease and vascular dementia in population-based studies
(2021-03-30)
Dementia, a clinical syndrome with several profiles and causes, is characterised by a decline in cognitive functions, including memory, learning, executive function, attention, language, and social ability. The most common ...
Pathophysiological role and clinical relevance of cytokines in hypertensive heart failure. A combined clinical and experimental study
(2007-12-06)
Although mortality due to heart failure has decreased significantly in the last decade since the introduction of ACE-inhibitors and β-adrenergic receptor blockers in the management of heart failure, chronic heart failure ...