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Microarray analysis of gene expression in human adipocytes and adipose tissue
(2008-02-21)
Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine ...
Molecular mechanisms in obesity-associated metabolic disease
(2007-07-12)
Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. This thesis ...
Adiponectin, the metabolic syndrome and atherosclerosis. Observation and intervention studies
(2006)
Adiponectin (Adn) has beneficial effects on insulin- and glucose metabolism as well as anti-inflammatory properties. High Adn concentrations are associated with reduced risks for insulin resistance and future diabetes, and ...
FOXC2 : a regulator of adipocyte metabolism
(2002)
Obesity, hyperlipidemia and insulin resistance are common forerunners of type 2 diabetes, a serious and increasingly prevalent disease in both the industrialised part of the world as well as in third world countries. We ...