Search
Now showing items 1-4 of 4
Genes implicated in the development of obesity and obesity-related disease
(2001)
Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes ...
IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice
(2016-01-29)
It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ...
Body fat regulating neuropeptides: relation to interleukines and gut microbiota
(2012-05-25)
Previous studies have shown that mice lacking interleukin-6 (IL-6), an important cytokine in the immune system, develop obesity, and that central, but not peripheral, administration of IL-6 induces energy expenditure. These ...
Cytokines in Metabolic Functions
(2008-02-28)
During infections, circulating cytokines are largely produced by immune cells. In healthy obese individuals, large parts of these circulating cytokines are produced in adipose tissue, for instance by macrophages that have ...