Search
Now showing items 1-10 of 22
Microarray analysis of gene expression in human adipocytes and adipose tissue
(2008-02-21)
Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine ...
Molecular mechanisms in obesity-associated metabolic disease
(2007-07-12)
Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. This thesis ...
Cardiovascular and metabolic control in obese children and adolescents
(2008-05-23)
Childhood obesity is an emerging risk factor for disease and mortality worldwide. The cardiovascular consequences and prevention thereof need to be further investigated. Exercise and weight loss are well examined and ...
Coping and personality in the obese. Results from the Swedish Obese Subjects Study
(2003)
The overall aims of this thesis were to evaluate coping and personality in obesity and the relation to weight change. Specific aims were to validate methods for assessing condition-specific coping and distress; to evaluate ...
Risk factors in ischemic stroke
(2005)
Ischemic stroke is a complex disease in which environmental and genetic factors make about equal contributions to the etiology. However, knowledge regarding the molecular basis of the genetic influence and the impact of ...
Genes implicated in the development of obesity and obesity-related disease
(2001)
Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes ...
The role of maternal nutrition and hormones in the regulation of placental nutrient transport and fetal growth
(2007)
Maternal nutrition during pregnancy is an important determinant of fetal growth. Undernutritionmay cause intrauterine growth restriction (IUGR), whereas increased nutrient availability, such asseen in obese women, often ...
Metabolic effects of interleukin-6
(2005)
The levels of the cytokine interleukin-6 (IL-6) in the circulation are positively correlated with indices of obesity and metabolic disturbances. Paradoxically, plasma IL-6 levels increase markedly during prolonged and ...