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Genetic Analyses of Tumor Progression in Colorectal Cancer
(2009-05-20)
Colorectal tumors are responsible for more than 600 000 deaths per year worldwide and thereby constitute the second most common cause of cancer related mortality. Early detection is related to improved prognosis and ...
Mechanisms of Osseointegration: Experimental Studies on Early Cellular and Molecular Events in vivo
(2010-06-14)
The early cellular and molecular activities determining the early tissue response and bone formation at bone/implant interface are not fully understood. The general aim of the current thesis was to develop a model for ...
On loading protocols and abutment use in implant dentistry. Clinical studies.
(2016-02-09)
ABSTRACT
Research questions: The influence of immediate or delayed loading and the use of abutments in implant dentistry with regard to peri-implant tissues and the effect of risk parameters.
Methodology: Fifty partially ...
From 1p3 to PI3K - Studies of neuroblastoma
(2011-01-19)
Neuroblastoma (NB) is a tumor of the sympathetic nervous system and is the most common extra-cranial tumor of childhood, accounting for 7% of all pediatric malignancies. Despite recent advances in therapeutics, outcome is ...
Experimental studies of the regulations of synthesis and release of tissue-type plasminogen activator from vascular endothelium
(2000)
The fibrinolytic system has several important functions and one crucial function is the prevention and removal of fibrin deposits in blood vessels. Tissue-type plasminogen activator (t-PA) plays a key role in this process, ...
Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials
(2015-09-15)
The mechanisms of guided bone regeneration (GBR) and bone healing with calcium phosphate (CaP) bone substitutes are not fully understood. The major aim of this thesis was to determine the relationship between the bone ...
Transcriptional profiling of human embryonic stem cells and their functional derivatives
(2010-10-07)
Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. ...
On the importance of inflammation for personality traits and psychiatric morbidity
(2010-12-10)
Background: Pro-inflammatory mediators have been implicated in processes that could be both beneficial and toxic to cells in the brain. On the one hand balanced levels of these mediators favour e.g. neurodevelopmental ...
Functional analysis of the -1087 single nucleotide polymorphism in the IL-10 promoter region.
(2010-11-15)
Interleukin (IL) 10 is recognized as a pro-inflammatory cytokine that promotes B cell proliferation. The objectives of the present series of studies were to analyze (i) differences in transcription factor binding to the ...
Molecular characterization of type I endometrial carcinomas
(2009-02-10)
Endometrial carcinoma is the most common malignancy in the female reproductive tract.
In Sweden over 1300 women are diagnosed every year, and although the prognosis is
favourable in the majority of cases, about 160 ...