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Multi-level characterization of host and pathogen in Helicobacter pylori-associated gastric carcinogenesis
(2014-11-06)
Today, more than half of the world’s population is infected with Helicobacter pylori, and two to three per cent of these will develop gastric cancer associated with this infection. Gastric cancer is today the third largest ...
Att vara syskon till ett barn eller ungdom med cancersjukdom - Tankar, behov, problem och stöd
(2009-05-12)
The overall aim was to describe the siblings’ thoughts on and experiences of needs, problems and supports when their brother or sister is being treated or undergoing follow-ups for or has died of cancer.
The thesis uses ...
Asthma and cancer among pulp and paper mill workers
(2002)
There were two main aims of this thesis. One was to study if repeated high exposures to irritant gases give rise to new-onset asthma, and the other was to study if exposure in pulp and paper mills were associated with ...
Intravoxel incoherent motion modeling - Optimization of acquisition, analysis and tumor tissue characterization
(2018-09-13)
Intravoxel incoherent motion (IVIM) analysis provides a means to obtain information on diffusion and perfusion from a single MRI sequence. The measurements are completely noninvasive and the results have been shown to be ...
Mediator and cell cycle regulation
(2015-11-04)
The multiprotein Mediator complex is an evolutionarily conserved coregulator of eukaryotic transcription. Mediator functions as a bridge between gene-specific transcription factors and the RNA polymerase II transcription ...
Genetic studies of neuroblastoma with emphasis on the apoptotic pathway
(2004)
Aim: The objective of this thesis was to find genes and chromosomal regions involved in neuroblastoma (NB) tumor progression. NB is a childhood tumor of the sympathetic nervous system that generally occurs spontaneously. ...
Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C. elegans
(2021-10-29)
Cancer is a major cause of mortality throughout the world. Despite the effort of the scientific community, plenty remains to understand about the biology or genetics of cancer. In solid tumors often as many as 90-99% of ...
Cancer in organ transplant recipients
(2021-08-27)
Tens of thousands of transplantations are performed around the world each year. Organ transplant recipients (OTR) are obliged to receive life-long medical treatment with immunosuppressive drugs to ensure graft function. ...