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Genetics of Parkinson's disease - with focus on genes of relevance for inflammation and dopamine neruon development
Please use this identifier to cite or link to this item:
http://hdl.handle.net/2077/21538
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| gupea_2077_21538_2.pdf | Abstract | 62Kb | Adobe PDF |  View/Open |
| gupea_2077_21538_1.pdf | Thesis frame | 625Kb | Adobe PDF | View/Open |
| Title: | Genetics of Parkinson's disease - with focus on genes of relevance for inflammation and dopamine neruon development |
| Authors: | Zettergren, Anna |
| Email: | anna.zettergren@pharm.gu.se |
| Issue Date: | 2010 |
| University: | University of Gothenburg. Sahlgrenska Academy |
| Department: | Institute of Neuroscience and Physiology. Department of Pharmacology |
| Parts: | I. Westberg L, Håkansson A, Melke J, Shahabi HN, Nilsson S, Buervenich S, Carmine A, Ahlberg J, Grundell MB, Schulhof B, Klingborg K, Holmberg B, Sydow O, Olson L, Johnles EB, Eriksson E, Nissbrandt H. Association between the estrogen receptor beta gene and age of onset of Parkinson’s disease. Psychoneuroendocrinology 2004; 29: 993-998. VIEW ARTICLE II. Håkansson A, Westberg L, Nilsson S, Buervenich S, Carmine A, Holmberg B, Sydow O, Olson L, Johnels B, Eriksson E, Nissbrandt H. Interaction of polymorphisms in the genes encoding interleukin-6 and estrogen receptor beta on the susceptibility to Parkinson’s disease. American Journal. of Medical Genetics (Part B) 2005; 13: 88-92. VIEW ARTICLE III. Håkansson A, Westberg L, Nilsson S, Buervenich S, Carmine A, Holmberg B, Sydow O, Olson L, Johnels B, Eriksson E, Nissbrandt H. Investigation of genes coding for inflammatory components in Parkinson’s disease. Movement Disorders 2005; 20: 569-573. VIEW ARTICLE IV. Håkansson A, Bergman O, Chrapkowska C, Westberg L, Carmine Belin A, Sydow O, Johnels B, Olson L, Holmberg B, Nissbrandt H. Cyclooxygenase-2 polymorphisms in Parkinson’s disease. American Journal of Medical Genetics (Part B) 2007; 144: 367-369. VIEW ARTICLE V. Håkansson A, Carmine Belin A, Stiller C, Sydow O, Johnels B, Olson L, Holmberg B, Nissbrandt H. Investigation of genes related to familial forms of Parkinson’s disease - With focus on the Parkin gene. Parkinsonism and Related Disorders 2008; 14: 520-522. VIEW ARTICLE VI. Bergman O, Håkansson A, Westberg L, Nordenström K, Carmine Belin A, Sydow O, Olson L, Holmberg B, Eriksson E, Nissbrandt H. PITX3 polymorphism is associated with early onset Parkinson’s disease. Neurobiology of Aging 2010; 31: 114-117. VIEW ARTICLE VII. Bergman O, Håkansson A, Westberg L, Carmine Belin A, Sydow O, Olson L, Holmberg B, Fratiglioni L, Bäckman L, Eriksson E, Nissbrandt H. Do polymorphisms in transcription factors LMX1A and LMX1B influence the risk for Parkinson’s disease? Journal of Neural Transmission 2009; 116: 333-338. VIEW ARTICLE |
| Date for public defence: | 2010-03-11 |
| Public defence: | Torsdagen den 11 mars 2010, kl. 13.00, Föreläsningssalen Ivan Östholm, LNC, Medicinaregatan 13 |
| Examinationsnivå: | Doctor of Philosophy (Medicine) |
| Publication type: | Doctoral thesis |
| Keywords: | Parkinson's disease genetics inflammation single nucleotide polymorphism dopamine neuron development estrogen gene age of onset Pitx3 estrogen receptor beta interleukin 6 |
| Abstract: | Abstract GENETICS OF PARKINSON’S DISEASE - WITH FOCUS ON GENES OF RELEVANCE FOR INFLAMMATION AND DOPAMINE NEURON DEVELOPMENT Introduction: The risk to be affected by Parkinson’s disease (PD) is considered to be influenced by genetic factors. In some rare cases of familial PD, mutations in some specific genes are known to cause the disease, but in the more common sporadic form of PD the causes are probably environmental factors interacting with genetic vulnerability. The main objective o... more |
| ISBN: | 978-91-628-8022-4 |
| URI: | http://hdl.handle.net/2077/21538 |
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